Stay near the banks of the Ohio and Mississippi rivers at the Quality Inn hotel in Cairo, Illinois. The hotel's location off Interstate 57 provides convenient access to Fort Defiance State Park, Wickliffe Mounds State Park, Magnolia Manor, Birds Blue Hole and Cypress Creek National Wildlife Refuge. At the hotel, you’ll appreciate features and amenities that include free wireless high-speed Internet access, free hot breakfast and coffee, free local calls, seasonal outdoor pool and pet-friendly hotel; fees apply. Take care of business on the go with our copy and fax services, or enjoy the scenery at our outdoor picnic area. Guest rooms are spacious and feature amenities such as microwaves, refrigerators, hair dryers, expanded cable television with HBO. The proximity to the neighboring states of Missouri and Kentucky provide even more to see and do. Explore Cairo’s historic district, where you’ll find the Old Custom House, a former post office and courthouse that now serves as a museum. Several shops and restaurants are also close by.